OraVerse® Patient Brochure
Learn more about reversing numbness after local anesthetic with a vasoconstrictor and ask your dentist if OraVerse is right for you.
OraVerse is indicated for the reversal of soft-tissue anesthesia, i.e., anesthesia of the lip and tongue, and the associated functional deficits resulting from an intraoral submucosal injection of a local anesthetic containing a vasoconstrictor.
OraVerse is not recommended for use in children less than 6 years of age or weighing less than 33 lbs.
Important Safety Information
In clinical trials, the most common adverse events with OraVerse (phentolamine mesylate) were post procedural pain, injection site pain, increased or decreased heart rate and headache. Following injections of phentolamine in non-dental procedures, substantial decreases in blood pressure have occurred which resulted in heart attacks as well as spasms and blocked blood vessels in the brain. Although such effects are uncommon with OraVerse, you should alert your doctor if you experience an increase in heart rate or abnormal heart rhythm (palpitations), particularly if you have a history of heart disease.
See full prescribing information for details.
